Virtual Human Platform for Safety Assessment – VHP4Safety


The VHP4Safety consortium consists of leading scientific groups from Dutch universities, university medical centres, public health institutes and applied research organisations, with expertise spanning the technological, biological, chemical, medical as well as the social sciences. The co-funders and cooperation partners ensure the active involvement of diverse academic, regulatory, industrial and societal partners to the project throughout the entire safety assessment knowledge chain. As such, the consortium unites necessary and complementary expertise to build, test and evaluate the Virtual Human Platform for Safety Assessment.

Leading partners

Utrecht University
HU University of Applied Sciences Utrecht aims to contribute to the innovation and professionalisation of professional practice and talent development, adding to the social, cultural and economic growth towards an open, just and sustainable society.
RIVM, the dutch National Institute for Public Health and the Environment is committed to a healthy population living in a healthy, safe environment.


At Amsterdam UMC more than 16,000 professionals work on complex patient care and the highly specialized treatment of rare diseases.

Cosmetics Europe is the European trade association for the cosmetics and personal care industry. Our members include cosmetics and personal care manufacturers as well as associations representing our industry at national level, right across Europe.
Charles River Laboratories (CRL) is a global Contract and Research Organization with multiple facilities in the Netherlands.
The Dutch Burns Foundation is a ANBI charity that supports the needs of all patients and relatives with skin burns.
The Dutch Association Innovative Medicines (VIG) is the industry association of pharmaceutical and vaccine companies in the Netherlands. The more than forty members focus on the development and marketing of innovative medicines. Medicines that ensure that we can work, care, and enjoy life. The members of the VIG are working on the medicines of tomorrow, for diseases for which there is currently no suitable treatment
Erasmus MC is the largest university medical centre of the Netherlands covering all specialities. The Department of Internal Medicine has a strong background in studying endocrine determinants of disease, both clinically and experimentally. The Thyroid Laboratory as part of the Erasmus MC Academic Center for Thyroid Diseases combines basic molecular biology studies on regulation of thyroid hormone action with epidemiological studies analyzing consequences of thyroid dysfunction in large cohorts and international collaborations. Members of the laboratory have a broad range of expertise, ranging from biochemistry and clinical endocrinology to genetic and clinical epidemiology.
Bridging Science to Practice – Our scientific findings and resulting practical innovations contribute worldwide to a safe & sustainable water provision
Leiden University
The ministry of Agriculture, Nature and Food Quality (LNV) coordinates a programme to accelerate animal-free innovation (TPI) in collaboration with other ministries and scientific, social and industrial partners.
The Department of Bioinformatics at Maastricht University focuses on the development and application of Integrative Systems Biology approaches in various research fields.
For over 50 years, the Dutch Kidney Foundation (Nierstichting Nederland) focuses its activities on kidney patients in the Netherlands. Central goal is improving the quality of life of kidney patients. The Dutch Kidney Foundation supports scientific research into causes, prevention and improved treatment of kidney disease and kidney failure.
ORTEC provides customized data-driven solutions for medical care and science to develop and productize clinical-decision support tools for personalized medicine.
Proefdiervrij is the Dutch Society for the Replacement of Animal Testing. They promote animal-free innovation and join forces for a future without animal testing.
Certara UK, Simcyp, develops physiologically-based pharmacokinetic models, in vitro pharmacokinetic models, quantitative systems toxicology models, and provides corresponding simulation tools.
Galapagos discovers, develops, and commercializes small molecule medicines with novel modes of action. Our pipeline comprises discovery through Phase 3 programs in inflammation, fibrosis, and other indications. Our ambition is to become a leading global biopharmaceutical company focused on the discovery, development, and commercialization of innovative medicines.
TNO connects people and knowledge to create innovations that boost the competitive strength of industry and well-being of society sustainably.
UMC Utrecht is a leading international university medical center generating, testing, sharing, and applying knowledge on health, illness, and health care for the benefit of patients and society.
On any given day, 2.5 billion people use Unilever products. Our range of more than 400 brands (including Dove, Knorr, Axe, Hellmann’s and Omo) give us a unique place in the lives of people all over the world. Unilever’s purpose and business strategy are to make sustainable living commonplace.
Vrije Universiteit (VU) Amsterdam is an academic organization providing scientific research, education and valorisation, strongly linked to people and society.
Wageningen University & Research is a collaboration between Wageningen University and the Wageningen Research foundation. Together we work on our mission: ‘To explore the potential of nature to improve the quality of life’ Over 6,500 employees and 12,500 students from more than hundred countries work everywhere around the world in the domain of healthy food and living environment for governments and the business community-at-large. The strength of Wageningen University & Research lies in its ability to join the forces of specialized research institutes and the university. It also lies in the combined efforts of the various fields of natural and social sciences. This union of expertise leads to scientific breakthroughs that can quickly be put into practice and be incorporated into education. This is the Wageningen Approach.


  • CBG
  • DTL
  • EC-JRC
  • hDMT
  • iVPH
  • SURFsara
  • Uppsala University
  • US-EPA
  • VUB